Liquid Chromatography-Mass Spectrometry (LC-MS)：

Waters SQ Detector 2 (SQD2) is a single quadrupole mass analyzer designed for the routine,

prepared for the unexpected. With a mass range of 3000 Da, SQD2 makes mass confirmation of large molecules

easier than ever before, allowing to see higher mass peaks and giving more confidence in the mass assignments.

SQD2 can simultaneously record positive and negative ions produced by electrospray ionization (ESI) mode.

Waters ACQUITY ARC System is the next generation of chromatography systems,

designed to provide superior performance and reliability.

The Arc HPLC system here is equipped with C-18 column for sample separation. 

For LC-MS analysis working, it is worth noting that samples require to eliminate particles and salt matrix effect first,

otherwise sample impurities often contribute to column contamination.